Intracoronary versus intravenous injection of 99mTc-tetrofosmin: comparison of myocardial perfusion patterns and wall motion

Basoglu T., Canbaz F., Sahin M., Elcik M., Kirtiloglu B., Sahin M., ...Daha Fazla

NUCLEAR MEDICINE COMMUNICATIONS, cilt.25, sa.5, ss.469-474, 2004 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 25 Sayı: 5
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1097/00006231-200405000-00007
  • Dergi Adı: NUCLEAR MEDICINE COMMUNICATIONS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.469-474
  • Anahtar Kelimeler: Tc-99m-tetrofosmin, SPECT, intracoronary injection, EMISSION COMPUTED-TOMOGRAPHY, TC-99M TETROFOSMIN, CORONARY-ANGIOGRAPHY, VIABLE MYOCARDIUM, TL-201, SPECT, TECHNETIUM-99M-TETROFOSMIN, STRESS, SCINTIGRAPHY, INFARCTION
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Objectives The accuracy of viability and defect size detection by Tc-99m-tetrofosmin has been discussed by several authors. The lower myocardial extraction fraction of the latter compared with Tc-99m-sestamibi or (TI)-T-201 has often been emphasized. We hypothesized that the intracoronary (i.c.) injection of tracer activity, i.e. higher than that theoretically achievable in the case of intravenous (i.v.) administration, could demonstrate the clinical relevance of this finding intra-individually. In this study, myocardial perfusion images obtained after tracer injection down the infarct-related artery were compared with i.v. injection images in the same patients. The trial also provided us with the opportunity to compare the wall motion values calculated using conventional Tc-99m-tetrofosmin Elated single-photon emission computed tomography (SPECT) studies with those obtained using optimal target/background ratios after i.c. injection.