Analysis of vitamin D receptor gene polymorphisms in patients with chronic periodontitis
INDIAN JOURNAL OF MEDICAL RESEARCH, cilt.127, sa.1, ss.58-64, 2008 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 127 Sayı: 1
- Basım Tarihi: 2008
- Dergi Adı: INDIAN JOURNAL OF MEDICAL RESEARCH
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.58-64
- Anahtar Kelimeler: chronic periodontitis, genotypes, polymorphism, vitamin D receptor, BONE-MINERAL DENSITY, D-RESISTANT RICKETS, RISK-FACTORS, JAPANESE PATIENTS, ASSOCIATION, POPULATION, ALLELES, SUSCEPTIBILITY, PROMOTER, MUTATION
- Ondokuz Mayıs Üniversitesi Adresli: Evet
Özet
Background & objectives: Genetic polymorphisms in the vitamin D receptor (VDR) gene are related to bone mineral density, bone turnover, and diseases with bone loss. Alveolar bone loss is a key feature in periodontitis. The aim of this study was to determine whether severe generalized chronic periodontitis (CP) in a Turkish population was associated with polymorphisms in the VDR gene.