Analysis of vitamin D receptor gene polymorphisms in patients with chronic periodontitis

Güneş S., Sumer A. P., Keles G. C., Kara N., Koprulu H., Bagci H., ...Daha Fazla

INDIAN JOURNAL OF MEDICAL RESEARCH, cilt.127, sa.1, ss.58-64, 2008 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 127 Sayı: 1
  • Basım Tarihi: 2008
  • Dergi Adı: INDIAN JOURNAL OF MEDICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.58-64
  • Anahtar Kelimeler: chronic periodontitis, genotypes, polymorphism, vitamin D receptor, BONE-MINERAL DENSITY, D-RESISTANT RICKETS, RISK-FACTORS, JAPANESE PATIENTS, ASSOCIATION, POPULATION, ALLELES, SUSCEPTIBILITY, PROMOTER, MUTATION
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Background & objectives: Genetic polymorphisms in the vitamin D receptor (VDR) gene are related to bone mineral density, bone turnover, and diseases with bone loss. Alveolar bone loss is a key feature in periodontitis. The aim of this study was to determine whether severe generalized chronic periodontitis (CP) in a Turkish population was associated with polymorphisms in the VDR gene.