The Antinociceptive Effects of Intravenous Dexmedetomidine in Colorectal Distension-Induced Visceral Pain in Rats: The Role of Opioid Receptors

Ülger F., Bozkurt A., Bilge S. S., Ilkaya F., Dilek A., Bostanci M. O., ...Daha Fazla

ANESTHESIA AND ANALGESIA, cilt.109, sa.2, ss.616-622, 2009 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 109 Sayı: 2
  • Basım Tarihi: 2009
  • Doi Numarası: 10.1213/ane.0b013e3181a9fae2
  • Dergi Adı: ANESTHESIA AND ANALGESIA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.616-622
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

BACKGROUND: In comparison with cutaneous pain, the role of alpha(2)-adrenoceptor (alpha(2)-AR) agonists in visceral pain has not been extensively examined. We aimed to characterize the antinociceptive effect of IV dexmedetomidine on visceral pain in rats and to determine whether antinociception thus produced is mediated by opioid receptors.