The Antinociceptive Effects of Intravenous Dexmedetomidine in Colorectal Distension-Induced Visceral Pain in Rats: The Role of Opioid Receptors

Ülger F., Bozkurt A., Bilge S. S., Ilkaya F., Dilek A., Bostanci M. O., ...More

ANESTHESIA AND ANALGESIA, vol.109, no.2, pp.616-622, 2009 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 109 Issue: 2
  • Publication Date: 2009
  • Doi Number: 10.1213/ane.0b013e3181a9fae2
  • Journal Name: ANESTHESIA AND ANALGESIA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.616-622
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

BACKGROUND: In comparison with cutaneous pain, the role of alpha(2)-adrenoceptor (alpha(2)-AR) agonists in visceral pain has not been extensively examined. We aimed to characterize the antinociceptive effect of IV dexmedetomidine on visceral pain in rats and to determine whether antinociception thus produced is mediated by opioid receptors.