Lack of association of the CD14/C-159T polymorphism with susceptibility and progression parameters in Turkish multiple sclerosis patients

Kurne A., Sayat G., Aydin O. F., Turgutoglu N., Terzi M., Sackesen C., ...More

JOURNAL OF NEUROIMMUNOLOGY, vol.250, no.1-2, pp.83-86, 2012 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 250 Issue: 1-2
  • Publication Date: 2012
  • Doi Number: 10.1016/j.jneuroim.2012.05.005
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.83-86
  • Keywords: Multiple sclerosis, RRMS, Soluble CD14, CD14 polymorphism, Progression index, SOLUBLE CD14, GENE, DISABILITY, RECEPTOR, PROMOTER, BLOOD
  • Ondokuz Mayıs University Affiliated: Yes


Soluble (s) CD14, being a receptor for lipopolysaccharides (LPSs) may inhibit LPS-triggered apoptosis and T lymphocyte proliferation. C to T exchange at position - 159 in the promoter region of the CD14 gene might lead to higher sCD14 levels.