Lifesaving dose increment of cabergoline in life-threatening spontaneous ovarian hyperstimulation syndrome resistant to all interventions
GYNECOLOGICAL ENDOCRINOLOGY, cilt.35, sa.4, ss.287-289, 2019 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 35 Sayı: 4
- Basım Tarihi: 2019
- Doi Numarası: 10.1080/09513590.2018.1525703
- Dergi Adı: GYNECOLOGICAL ENDOCRINOLOGY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
- Sayfa Sayıları: ss.287-289
- Anahtar Kelimeler: Spontaneous ovarian hyperstimulation syndrome, singleton pregnancy, pregnancy termination, cabergoline, DOPAMINE AGONIST CABERGOLINE, ASSISTED REPRODUCTION, WOMEN, STIMULATION, MUTATION, RECEPTOR, PREVENT, TORSION
- Ondokuz Mayıs Üniversitesi Adresli: Evet
Özet
Objective: Spontaneous ovarian hyperstimulation syndrome (SOHSS) is an extremely rare complication that deserves a multidisciplinary approach together with a thorough investigation for the correct diagnosis of the underlying pathology. The aim of this study was to present a case of severe SOHSS resistant to all interventions and to discuss the available interventions to overcome such a rare and serious clinical situation. Case report: We report a case of severe, life-threatening spontaneous OHSS with a normal nine weeks singleton pregnancy in a 25-year-old nulliparous woman, which resulted with pregnancy termination and continuation of disease progression until the dose of cabergoline was increased to 1.5 mg/day. Conclusion: This case report emphasizes that patients with life-threatening SOHSS resistant to all medical and surgical interventions may benefit from higher doses of cabergoline. Although spontaneous OHSS is extremely rare, it is potentially a life-threatening clinical entity in its severe form and needs time management and detailed examination of the underlying causes.