Fatal sepsis in a child with thalassemia major due to Serratia marcescens

Paksu M. S., Karli A., Paksu S., Guney A. K., Ozsevik S. N., Belet N.

PEDIATRICS INTERNATIONAL, vol.56, no.5, pp.796-797, 2014 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 56 Issue: 5
  • Publication Date: 2014
  • Doi Number: 10.1111/ped.12492
  • Journal Name: PEDIATRICS INTERNATIONAL
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.796-797
  • Keywords: sepsis, Serratia, splenectomy, thalassemia major, INFECTIONS, DEATH
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

One of the most important causes of mortality in thalassemic patients is infectious disease. Thalassemic patients develop severe invasive infection caused by microorganisms that are rare in healthy individuals. We describe the case of a 13-year-old splenectomized boy who presented with septic shock and who died 36h after admission, despite broad-spectrum antibiotics and aggressive supportive care. Serratia marcescens was isolated from cultures of blood and tracheal aspirate. It is known that rare microorganisms will cause severe community-acquired infection in splenectomized patients with thalassemia major.