Effect of colchicine on experimental acetic acid induced colitis

Yildirim B., Tuncer C., Sahin D., Dinel A. S., UYAR GÖÇÜN F. P., Leventoglu S., ...Daha Fazla

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, cilt.39, sa.1, ss.63-69, 2014 (SCI-Expanded, Scopus, TRDizin) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 1
  • Basım Tarihi: 2014
  • Doi Numarası: 10.5505/tjb.2014.49354
  • Dergi Adı: TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.63-69
  • Anahtar Kelimeler: Colchicine, ulcerative colitis, experimental model, FAMILIAL MEDITERRANEAN FEVER, INFLAMMATORY-BOWEL-DISEASE, MONOSODIUM URATE CRYSTALS, ULCERATIVE-COLITIS, RATS, REDUCTION, MECHANISM, APOPTOSIS, DAMAGE, MEFV
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Objectives: Ulcerative colitis (UC) is an inflammatory disease of the colonic mucosa with involvement from distal to proximal and characterized by neutrophil infiltration. There is no golden standart for the current state of therapy of the patients with UC. The aim of this study is to evaluate the possible effects of colchicine against acetic acid (AA)-induced colitis in rats.