The assessment of the serum levels of TWEAK and prostaglandin F2 alpha in COVID-19

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YALÇIN KEHRİBAR D., Cihangiroglu M., Sehmen E., Avcı B., Capraz M., Boran M., ...More

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.50, no.8, pp.1786-1791, 2020 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 50 Issue: 8
  • Publication Date: 2020
  • Doi Number: 10.3906/sag-2006-96
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.1786-1791
  • Keywords: COVID-19, TWEAK, leukotrienes, inflammation, prostaglandin, WEAK INDUCER, CYTOKINE, RECEPTOR, PATHWAY, LUPUS, MONTELUKAST, INDUCTION, APOPTOSIS, DISEASE
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Background/aim: It is claimed that aberrant immune response has a more important role than the cytopathic effect of the virus in the morbidity and mortality of the coronavirus disease 2019 (COVID-19). We aimed to investigate the possible roles of tumor necrosis factor-like weak inducer of apoptosis (TWEA K)/Fn14 pathway and leukotrienes (LT) in uncontrolled immune response that occurs in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).