Two new colorimetric methods for early detection of vancomycin and oxacillin resistance in Staphylococcus aureus

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Coban A., Bozdogan B., Cihan C., Cetinkaya E., Bilgin K., Darka O., ...More

JOURNAL OF CLINICAL MICROBIOLOGY, vol.44, no.2, pp.580-582, 2006 (SCI-Expanded)

• Publication Type: Article / Article
• Volume: 44 Issue: 2
• Publication Date: 2006
• Doi Number: 10.1128/jcm.44.2.580-582.2006
• Journal Name: JOURNAL OF CLINICAL MICROBIOLOGY
• Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Page Numbers: pp.580-582
• Ondokuz Mayıs University Affiliated: Yes

Abstract

We developed two colorimetric methods for the detection of vancomycin- and oxacillin-resistant Staphylococcus aureus in <= 6 h: (i) a nitrate reductase assay and (ii) a resazurin microplate method. MICs agreed with results obtained by CLI methods for oxacillin. However, detection of vancomycin resistance required a larger inoculum. These methods may be recommended for the detection of vancomycin- and oxacillin-resistant S. aureus.