Anticancer, photoluminescence and electrochemical properties of structurally characterized two imine derivatives

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Ceyhan G., Köse M., Tümer M., Demirtaş İ.

Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy, cilt.149, ss.731-743, 2015 (SCI-Expanded, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 149
• Basım Tarihi: 2015
• Doi Numarası: 10.1016/j.saa.2015.05.021
• Dergi Adı: Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.731-743
• Anahtar Kelimeler: Anticancer, Electrochemistry, Photoluminescence, Schiff base
• Ondokuz Mayıs Üniversitesi Adresli: Hayır

Özet

Two imine compounds, 4-[(E)-(2-methoxybenzylidene)amino]phenol (L¹) and 4-[(E)-(3,4-dimethoxybenzylidene)amino]phenol (L²) were synthesized and characterized by the analytical and spectroscopic methods. The electrochemical and photoluminescence properties of the imine compounds L¹ and L² were investigated in different solvents. The compounds L¹ and L² show different redox processes at some potentials. The molecular structures of two Schiff base compounds are broadly similar, differing principally in the position, the number of methoxy (OCH3) groups and dihedral angles between aromatic rings. While the compound L¹ has only one methoxy group located on the o-position with respect to the imine bond (CN), the L² contains two methoxy groups on the p-m-positions with respect to the imine bond. The imine compounds show two or three emission bands in the 619-832 nm range in organic solvents. In the 1.0 × 10^-3 M concentration, the compounds have the highest excitation and emission bands. The imine compounds L¹ and L² were screened for their in vitro cytotoxicity on HeLa cell lines using the xCELLigence system (Real Time Cell Analyzer).