Does ADMA affect the oxidant/antioxidant balance in rats?

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Alacam H., Avcı B., Salis O., Dilek A., Kozan A., MERTOĞLU C., ...More

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.43, no.3, pp.405-410, 2013 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 3
  • Publication Date: 2013
  • Doi Number: 10.3906/sag-1206-11
  • Journal Name: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.405-410
  • Keywords: Asymmetric dimethylarginine, malondialdehyde, superoxide dismutase, glutathione peroxidase, NITRIC-OXIDE SYNTHASE, ASYMMETRIC DIMETHYLARGININE, ENDOTHELIAL DYSFUNCTION, SUPEROXIDE-PRODUCTION, PEROXYNITRITE, MECHANISMS, ASSAY
  • Ondokuz Mayıs University Affiliated: Yes

Abstract

Aim: Asymmetric dimethylarginine (ADMA) is an inhibitor of nitric oxide synthase (NOS). Oxidative stress might be defined as an imbalance between protein oxidation and antioxidants. Our aim was to determine in vivo whether ADMA causes oxidative damage.