Synthesis, crystal structure, spectral and thermal characterization, and antimicrobial activity of [Cu(HOr)(aepy)(H2O)]center dot H2O (aepy=2-aminoethylpyridine, HOr(2-)=orotate)

YEŞİLEL O. Z., DEGE N., Darcan C., Bueyuekguengoer O.

ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES, cilt.62, sa.12, ss.1590-1594, 2007 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 62 Sayı: 12
  • Basım Tarihi: 2007
  • Dergi Adı: ZEITSCHRIFT FUR NATURFORSCHUNG SECTION B-A JOURNAL OF CHEMICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1590-1594
  • Anahtar Kelimeler: orotate complex, vitamin B13, 2-aminoethyl pyridine, antimicrobial activity, OROTIC-ACID, VITAMIN-B13 COMPLEXES, MONOHYDRATE, NICKEL(II), COPPER(II)
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

The copper(II) orotate complex with 2-aminoethylpyridine, [Cu(HOr)(aepy)(H2O)] center dot H2O, was synthesized and characterized by means of elemental and thermal analysis, magnetic susceptibility, IR and UV/vis spectroscopic, single crystal X-ray diffraction, and antimicrobial activity studies. The complex crystallizes in the triclinic system, space aroup P (1) over bar, and the Cu(II) ion is five-coordinate with a distorted square-pyramidal coordination geometry. The aepy ligand and the orotate dianion behave as bidentate (N,N' and N,O-acid) chelating ligands. The crystal structure is stabilized by intermolecular O-H center dot center dot center dot O and N-H center dot center dot center dot O hydrogen bonds, and the orotate ligand exhibits a double hydrogen-bonding functionality. The new compound was found active against some gram (+)/(-) bacteria and yeast Candida albicans ATCC 1023 1, but there was no activity on Aspergillus niger.