Iron-Induced Cerebellar Purkinje Cell Loss Is Ameliorated by Flunarizine

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Kozan R., Bostanci M. O., Nacar T., Aslan A., Bagirici F.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.39, sa.1, ss.37-42, 2009 (SCI-Expanded, Scopus, TRDizin) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 39 Sayı: 1
  • Basım Tarihi: 2009
  • Doi Numarası: 10.3906/sag-0712-2
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.37-42
  • Anahtar Kelimeler: Flunarizine, iron, neurotoxicity, Purkinje cell, stereology, RAT, MECHANISMS, CALCIUM, EXPOSURE, CHANNEL, NUMBER, DEATH
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

Aim: In this study, we investigated the effect of intracerebroventricular-injected iron neurotoxicity on the total number of cerebellar Purkiinje cells in rats and the possible neuroprotective effect of flunarizine, a piperazine-derived calcium channel blocker.