Novel saponins from Nigella arvensis var. involucrata

Bıçak K., Gülcemal D., Demirtaş İ., Alankuş Ö.

Phytochemistry Letters, vol.21, pp.128-133, 2017 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 21
  • Publication Date: 2017
  • Doi Number: 10.1016/j.phytol.2017.06.002
  • Journal Name: Phytochemistry Letters
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.128-133
  • Keywords: Nigella arvensis, Oleanane, Ranunculaceae, Saponins
  • Ondokuz Mayıs University Affiliated: No


Four new oleanane-type triterpene glycosides namely 3-O-[β-D-glucopyranosyl-(1 → 2)-β-D-glucopyranosyl-(1 → 2)-α-L-arabinopyranosyl] oleanolic acid, 3-O-[β-D-glucopyranosyl-(1 → 2)-β-D-glucopyranosyl-(1 → 2)-α-L-arabinopyranosyl]-28-O-[α-L-rhamnopyranosyl-(1 → 4)-β-D-glucopyranosyl-(1 → 6)-β-D-glucopyranosyl] oleanolic acid, 3-O-[β-D-quinovopyranosyl-(1 → 3)-α-L-rhamnopyranosyl-(1 → 2)-α-L-arabinopyranosyl]-28-O-[β-D-glucopyranosyl] oleanolic acid, 3-O-[β-D-quinovopyranosyl-(1 → 3)-α-L-rhamnopyranosyl-(1 → 2)-α-L-arabinopyranosyl]-28-O-[α-L-rhamnopyranosyl(1 → 4)-β-D-glucopyranosyl-(1 → 6)-β-D-glucopyranosyl] oleanolic acid, were isolated from methanol extract of the roots of Nigella arvensis var. involucrata along with five known oleanane-type triterpene glycosides and a steroid glucoside. Structures of the new compounds were established as by using 1D and 2D NMR techniques and mass spectrometry.