Preparation, Characterization, and Swelling Behavior of PEGylated Guar Gum @ Ag Nanoparticles


Karakuş S., Tan E., İlgar M., Kahyaoğlu İ. M., Şahin Y. M., Sezgin Mansuroğlu D., ...Daha Fazla

Sonochemical Reactions, Selcan Karakuş, Editör, IntechOpen, London, ss.3-13, 2020

  • Yayın Türü: Kitapta Bölüm / Araştırma Kitabı
  • Basım Tarihi: 2020
  • Yayınevi: IntechOpen
  • Basıldığı Şehir: London
  • Sayfa Sayıları: ss.3-13
  • Editörler: Selcan Karakuş, Editör
  • Ondokuz Mayıs Üniversitesi Adresli: Evet

Özet

In this study, polyethylene glycol/guar gum @ silver nanoparticles (PEG/GG@AgNPs) were synthesized by using simple sonication method. The nanoparticles were characterized using Fourier-transform infrared spectroscopy (FTIR) and scanning transmission electron microscopy (STEM). The swelling behaviors of nanoparticles were studied in different pHs (5.5 and 7.4). The experimental results were calculated by Fickian diffusion and Schott kinetic models to understand the swelling mechanism and coefficients of the nanoparticles. The results showed that the linear equation of the Fickian diffusion kinetic model was best fit to explain the water diffusion mechanism of the nanoparticle with high correlation coefficient (R2 = 0.982–0.987). The results confirmed that the swelling degree of nanoparticles were 9.71 g/g at pH 5.5. Also, the results confirmed that PEG/GG@AgNPs can be a good candidate for drug delivery systems in pharmaceutical applications.