Levels of platelet activating factor in gingival crevice fluid following periodontal surgical therapy

Keles G. C., Cetinkaya B. O., IŞILDAK İ., Koprulu H., Acikgoz G.

JOURNAL OF PERIODONTAL RESEARCH, vol.41, no.6, pp.513-518, 2006 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 6
  • Publication Date: 2006
  • Doi Number: 10.1111/j.1600-0765.2006.00898.x
  • Journal Name: JOURNAL OF PERIODONTAL RESEARCH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.513-518
  • Keywords: gingival crevice fluid, high-performance liquid chromatography, periodontal surgery, platelet activating factor, GUIDED TISSUE REGENERATION, ENDOTOXIN-INDUCED PERIODONTITIS, CONTROLLED CLINICAL-TRIAL, INTRABONY DEFECTS, BIOABSORBABLE MEMBRANE, BONE TURNOVER, SALIVARY PAF, COLLAGEN, BARRIER, RATS
  • Ondokuz Mayıs University Affiliated: No

Abstract

Background and Objective: Elevated levels of platelet activating factor (PAF), a potent inflammatory phospholipid mediator, have been previously detected in gingival tissues and gingival crevice fluid (GCF) in periodontal disease. However, the role of this mediator during wound healing after periodontal surgery remains unclear. The hypothesis, a relationship between PAF levels and periodontal healing, was tested by measuring PAF levels in GCF samples collected from sites that had undergone guided tissue regeneration (GTR) or flap surgery.