Nonsurgical Periodontal Therapy Reduces Salivary and Gingival Crevicular Fluid YKL-40 and IL-6 Levels in Chronic Periodontitis
ORAL HEALTH & PREVENTIVE DENTISTRY, cilt.18, sa.4, ss.815-822, 2020 (SCI-Expanded, Scopus)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 18 Sayı: 4
- Basım Tarihi: 2020
- Doi Numarası: 10.3290/j.ohpd.a45086
- Dergi Adı: ORAL HEALTH & PREVENTIVE DENTISTRY
- Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, PASCAL, CINAHL, EMBASE, MEDLINE
- Sayfa Sayıları: ss.815-822
- Anahtar Kelimeler: after-treatment, gingival crevicular fluid, human, interleukin-6, saliva, YKL-40 protein, EARLY RHEUMATOID-ARTHRITIS, REACTIVE PROTEIN-LEVELS, SERUM YKL-40, DISEASE, INTERLEUKIN-6, BIOMARKER, MARKER
- Ondokuz Mayıs Üniversitesi Adresli: Evet
Özet
Purpose: A novel acute-phase protein, YKL-40, is known as an inflammation-associated glycoprotein. YKL-40 is shown to be linked to inflammation, endothelial dysfunction and tissue remodeling secreted by various cells and is also considered to be stimulated by cytokines such as interleukin-6 (IL-6). The present study aimed to investigate YKL-40 and IL-6 levels in saliva and gingival crevicular fluid (GCF) of patients with chronic periodontitis (CP) after non-surgical periodontal therapy for the first time.