The Protective Effect of Adalimumab on Renal Injury in a Model of Abdominal Aorta Cross-Clamping

Cure, Medine; Cure, ERKAN; Kalkan, YILDIRAY; Tumkaya, Levent; Aydin, Ibrahim; Kirbas, AYNUR; Efe, HASAN; Kurt, AYSEL; YUCE, Suleyman

doi:10.17219/acem/33250

The Protective Effect of Adalimumab on Renal Injury in a Model of Abdominal Aorta Cross-Clamping

Cure M. C., Cure E., Kalkan Y., Tumkaya L., Aydin I., Kirbas A., ...Daha Fazla

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, cilt.25, sa.2, ss.219-226, 2016 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 25 Sayı: 2
Basım Tarihi: 2016
Doi Numarası: 10.17219/acem/33250
Dergi Adı: ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.219-226
Anahtar Kelimeler: ischemia, reperfusion injury, adalimumab, carbonic anhydrases, tumor necrosis factor alpha, CARBONIC-ANHYDRASE-II, ISCHEMIA-REPERFUSION, ISCHEMIA/REPERFUSION INJURY, RADICAL-ANION, BICARBONATE, INFLAMMATION, EXPRESSION, INTERLEUKIN-6, PRETREATMENT, INHIBITION
Ondokuz Mayıs Üniversitesi Adresli: Hayır

Özet

Background. Adalimumab (ADA) is a potent inhibitor of tumor necrosis factor (TNF-alpha). ADA treatment suppresses proinflammatory cytokines, leading to a decrease or inhibition of the inflammatory process.