Education
2005 - 2013
2005 - 2013Doctorate
Gebze Technical University, Fen Bilimleri Enstitüsü, Moleküler Biyoloji Ve Genetik (Dr), Turkey
2002 - 2005
2002 - 2005Postgraduate
Gebze Yüksek Teknoloji Enstitüsü, Mühendislik Ve Fen Bilimleri Enstitüsü, Biyoloji (Yl) (Tezli), Turkey
1997 - 2001
1997 - 2001Undergraduate
Mersin University, Fen-Edebiyat Fakültesi, Biyoloji Bölümü, Turkey
Dissertations
2013
2013Doctorate
Bacıllus thuringiensis subsp. Israelensis’xxin biyoinsektisid (endotoksin) üretme kapasitesinin arttırılması amacıyla fosfat metabolizmasının değiştirilmesi
Gebze Technical University, Fen Bilimleri Enstitüsü, Moleküler Biyoloji Ve Genetik (Dr)
2005
2005Postgraduate
Sivrisinek mücadelesinde sivrisinek larvalarına karşı kullanılabilecek mikroorganizmaların izolasyonu ve etkinliklerinin incelenmesi
Gebze Yüksek Teknoloji Enstitüsü, Mühendislik Ve Fen Bilimleri Enstitüsü, Biyoloji (Yl) (Tezli)
Research Areas
Life Sciences
Bioinformatics
Biotechnology
Microbiology
Molecular Biology and Genetics
Natural Sciences
Academic Positions
2022 - Present
2022 - PresentResearcher
Umea Universitet (Umea University)
2018 - Present
2018 - PresentAssistant Professor
Ondokuz Mayis University, Fen Fakültesi, Moleküler Biyoloji ve Genetik Bölümü
2002 - 2018
2002 - 2018Research Assistant
Gebze Technical University, Fen Bilimleri Enstitüsü
Managerial Experience
2020 - Present
2020 - PresentDeputy Head of Department
Ondokuz Mayis University
Non Academic Experience
2012 - 2014
2012 - 2014Doktora sonrası araştırmacı
Umea Üniversitesi/İSVEÇ, Doktora sonrası araştırmacı
Supervised Theses
2021
2021Doctorate
Effect of lon protease overexpression on endotoxin production and stress resistance in Bacillus thuringiensis
Tuğrul D. (Advisor)
M.ABDI(Student)
2019
2019Postgraduate
Lon proteaz geninin çoklu kopyalarının streptomyces coelıcolor A3(2)'de homolog ifadesi ve Esherichia coli 'de heterolog ifadesi üzerine çalışmalar
Tuğrul D. (Advisor)
H.YILMAZ(Student)
Articles
All (19)
SCI-E, SSCI, AHCI (18)
SCI-E, SSCI, AHCI, ESCI (19)
ESCI (1)
Scopus (19)
TRDizin (4)
2024
20241. Effects of Bacillus thuringiensis var. israelensis Strains and Toxins on the Pine Processionary Moth Thaumetopoea wilkinsoni (Lepidoptera: Notodontidae)
Topkara E., Yanar O., Doruk T., Terzi Y.
BIOLOGY BULLETIN
, vol.51, no.5, pp.1301-1311, 2024 (SCI-Expanded)
2024
20242. Synthesis, XRD, spectroscopic (UV-Vis, IR, EPR) and biological evaluations of cobalt(II)-ciprofloxacin complex as antimicrobial agent: In silico molecular docking and ADME
Aycan T., Öztürk F., Doruk T.
JOURNAL OF MOLECULAR STRUCTURE
, vol.1306, 2024 (SCI-Expanded)
2024
20243. A thermostable and acidophilic mannanase from Bacillus mojavensis: its sustainable production using spent coffee grounds, characterization, and application in grape juice processing
Cilmeli S., Doruk T., Könen-Adıgüzel S., Adıgüzel A. O.
BIOMASS CONVERSION AND BIOREFINERY
, vol.14, no.3, pp.3811-3825, 2024 (SCI-Expanded)
2023
20234. Partial characterization of ss-glucosidase, ss-xylosidase, and a-larabinofuranosidase from Jiangella alba DSM 45237 and their potential in lignocellulose-based biorefining
Aytas Z. G., Tunçer M., Kul C. S., Cilmeli S., Aydin N., Doruk T., et al.
SUSTAINABLE CHEMISTRY AND PHARMACY
, vol.31, 2023 (SCI-Expanded)
2022
20225. Efficacy of Diptera-targeted Bacillus thuringiensis var. israelensis against the pine processionary moth, Thaumetopoea wilkinsoni (Lepidoptera: Notodontidae)
Yanar O., Topkara E. F., Doruk T.
ARCHIVES OF PHYTOPATHOLOGY AND PLANT PROTECTION
, vol.55, no.13, pp.1530-1541, 2022 (ESCI, Scopus)
2021
20216. Effect of lon Protease Overexpression on Endotoxin Production and Stress Resistance in Bacillus thuringiensis
Barkad M. A., Bayraktar A., Doruk T., Tunca S.
CURRENT MICROBIOLOGY
, vol.78, no.9, pp.3483-3493, 2021 (SCI-Expanded)
2021
20217. Polyhydroxyalkanoate accumulation in Streptomyces coelicolor affected by SCO7613 gene region
Demir Oksuz Z., Doruk T., Yağcı N., Tunca Gedik S.
TURKISH JOURNAL OF BIOLOGY
, vol.45, no.3, pp.275-286, 2021 (SCI-Expanded)
2020
20208. Synthesis, structural, spectral and antimicrobial activity studies of copper-nalidixic acid complex with 1,10-phenanthroline: DFT and molecular docking
Aycan T., Öztürk F., Doruk T., Demir S., Fidan M., Padaoglu H.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
, vol.241, 2020 (SCI-Expanded)
2019
20199. Development, Optimization, and Validation of a High Throughput Screening Assay for Identification of Tat and Type II Secretion Inhibitors of Pseudomonas aeruginosa
Massai F., Saleeb M., Doruk T., Elofsson M., Forsberg A.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY
, vol.9, 2019 (SCI-Expanded)
2019
201910. Supercritical water oxidation of octol - containing wastewater
Gurbulak E., Yuksel E., Tekbas M., Doruk T., Eyvaz M., Bektas N.
GLOBAL NEST JOURNAL
, vol.21, no.2, pp.172-179, 2019 (SCI-Expanded)
2019
201911. Synthesis and characterization of antimicrobial polylactide via ring-opening polymerization and click chemistry methods
Aynali F., DOĞANCI E., Doruk T., SADIKOĞLU H.
POLYMER INTERNATIONAL
, vol.68, no.3, pp.385-393, 2019 (SCI-Expanded)
2018
201812. Comparative proteomic analysis of bacillus thuringiensis wild-type and two mutant strains disturbed in polyphosphate homeostasis
Yeşilirmak F., Doruk T., Yilmaz Ş., Tunca Gedik S.
Turkish Journal of Biology
, vol.42, no.1, pp.87-102, 2018 (SCI-Expanded)
2017
201713. The Tat substrate SufI is critical for the ability of Yersinia pseudotuberculosis to cause systemic infection
Avican U., Doruk T., östberg Y., Fahlgren A., Forsberg Å.
Infection and Immunity
, vol.85, no.4, 2017 (SCI-Expanded)
2016
201614. Naked-eye fluorescent sensor for Cu(II) based on indole conjugate BODIPY dye
Tümay S. O., Okutan E., Sengul I. F., Özcan E., Kandemir H., Doruk T., et al.
Polyhedron
, vol.117, pp.161-171, 2016 (SCI-Expanded)
2016
201615. High levels of polyphosphate kinase affect not only endotoxin production but also acid tolerance of bacillus thuringiensis
Doruk T., Girgin Ersoy Z., Öncel M. S., Tunca Gedik S.
Turkish Journal of Biology
, vol.40, no.6, pp.1168-1177, 2016 (SCI-Expanded)
2013
201316. Overexpression of polyphosphate kinase gene (ppk) increases bioinsecticide production by Bacillus thuringiensis
Doruk T., Avican U., Camci I. Y., Gedik S. T.
Microbiological Research
, vol.168, no.4, pp.199-203, 2013 (SCI-Expanded)
2013
201317. An efficient gene deletion system for Bacillus thuringiensis
Doruk T., Gedik S. T.
Biologia (Poland)
, vol.68, no.3, pp.358-364, 2013 (SCI-Expanded)
2012
201218. Deletion of polyphosphate kinase gene (ppk) has a stimulatory effect on actinorhodin production by streptomyces coelicolor A3(2)
Yalim Camci I., Doruk T., Avican Ü., Tunca Gedik S.
Turkish Journal of Biology
, vol.36, no.4, pp.373-380, 2012 (SCI-Expanded)
2011
201119. Further investigation of the mechanism of Vitreoscilla hemoglobin (VHb) protection from oxidative stress in Escherichia coli
Akbas M. Y., Doruk T., Ozdemir S., Stark B. C.
Biologia
, vol.66, no.5, pp.735-740, 2011 (SCI-Expanded)
Papers Presented at Peer-Reviewed Scientific Conferences
2022
20221. New Small Molecule Inhibits Pyoverdine Biosynthesis in Pseudomonas aeruginosa
Uyanık E., KUL Ç. S., ÇAĞLAR N., DORUK T.
FEMS Conference on Microbiology 2022, Belgrade, Serbia, 30 June - 02 July 2022, pp.340-341, (Full Text)
2022
20222. The Effects of PVDM Protein Deprivation on Virulence in Pseudomonas aeruginosa
Kul Ç. S., DORUK T.
9th International Istanbul Scientific Research Congress, İstanbul, Turkey, 14 - 15 May 2022, pp.168, (Summary Text)
2022
20223. Heterelog Expression, Purification and Characterization of Bacillus Mojavensis Th309 Sourced Pectate Lycase Enzyme in E. coli
Aydın N., DORUK T.
9th International Istanbul Scientific Research Congress, İstanbul, Turkey, 14 - 15 May 2022, pp.147, (Summary Text)
2022
20224. Screening of Potential Cutinase-Producing Clones in Metagenomic Libraries Constructed Using DNA Extracted from Microplastics
ŞEN F., CİLMELİ S., TUNÇER M., DORUK T., KÖNEN ADIGÜZEL S., KIDEYŞ A. E., et al.
2nd International Conference on Applied Engineering and Natural Sciences, Konya, Turkey, 10 March 2022, (Summary Text)
2019
20195. Co-Production of Pectinase, Cellulase and Xylanase by Thermophylic Aspergillus sp. 55SZ for Clafication of Fruit Juices.
ÇELİK T., YAĞIZ N., DORUK T., TUNÇER M., ADIGÜZEL A. O.
6th International Conference on Sustainable Agriculture and Environment, Konya, Turkey, 3 - 05 October 2019, pp.488-491, (Full Text)
2019
20196. Co-Production Of Pectinase, Cellulase And Xylanase By Thermophylic Aspergillus Sp. 55SZ For Clarifıcation Of Fruit Juıces.pp 488-491
ÇELİK T., DORUK T., TUNÇER M., ADIGÜZEL A. O.
6th International Conferance on Sustainable Agriculture and Environment., Konya, Turkey, 03 October 2019, pp.488-491, (Summary Text)
2019
20197. Antimikrobiyal Polilaktik Asit Filmlerin Hazırlanması ve Termal/Mekanik Özelliklerinin İncelenmesi
AYNALI F., DOĞANCI E., DORUK T., ÖZKOÇ G., SADIKOĞLU H.
31. Ulusal Kimya Kongresi, İstanbul, Turkey, 10 - 13 September 2019, pp.102, (Summary Text)
2018
20188. Novel Actinobacteria Strains with Antimicrobial and Antibiofilm Activities Isolated from Various Environmental Samples
ATEŞ H., AY H., DORUK T., ŞAHİN N.
2. Uluslararası UNIDOKAP Karadeniz Sempozyumu, Samsun, Turkey, 28 - 30 November 2018, (Summary Text)
2018
20189. Polyphasic Taxonomy of A Novel Actinomadura sp. 14C53, Isolated from Basaltic Parent Material
ATEŞ H., AY H., DORUK T., ŞAHİN N.
2nd International UNIDOKAP Black Sea Symposium on BIODIVERSİTY, 28 - 30 November 2018, pp.154, (Summary Text)
2018
201810. Comparison of Antibiotic Production Profile of Streptomyces coelicolor M145 Δppk andStreptomyces coelicolor A3(2) Δppk
DEMİR Ğ., BAYRAKTAR A., DEMİR ÖKSÜZ Z., DORUK T., TUNCA GEDİK S.
International Eurasian Conference onBiological and Chemical Sciences, Ankara, Turkey, 26 - 27 April 2018, (Summary Text)
2017
201711. Heterologous expression of Streptomyces coelicolor “relA” and “lon” genes in different Escherichia coli mutants
YILMAZ H., CESUR M. F., DEMİR ÖKSÜZ Z., DORUK T., TUNCA GEDİK S.
18th International Symposium on the Biology of Actinomycetes, Jeju, South Korea, 23 - 27 May 2017, (Summary Text)
2015
201512. Bacillus thuringiensis te polifosfat metabolizması ve ikincil metabolit üretimi arasındaki ilişki
DORUK T., YILMAZ Ş., DEDE YEŞİLIRMAK F., TUNCA GEDİK S.
Ulusal Biyoteknoloji Kongresi, Turkey, 18 - 19 December 2015, (Full Text)
2015
201513. Polifosfat sentezi ve yıkımından sorumlu enzimlerden yoksun Bacillus thuringiensis suşunda endotoksin biyosentezi
YEDEKÇİ A., DORUK T., TUNCA GEDİK S.
Ulusal Biyoteknoloji Kongresi, Turkey, 18 - 19 December 2015
2015
201514. Lactococcus lactis in Nisin Üretiminin Optimizasyonu
GİRGİN ERSOY Z., DORUK T., TUNCA GEDİK S.
Ulusal Biyoteknoloji Kongresi, Turkey, 18 - 19 December 2015
2015
201515. Yüksek miktardaki polifosfat sadece endotoksin biyosentezini değil Bacillus thuringiensis in asit direncini de arttırıyor
DORUK T., GİRGİN ERSOY Z., TUNCA GEDİK S.
Ulusal Biyoteknoloji Kongresi, Turkey, 18 - 19 December 2015, (Full Text)
2015
201516. Role of twin arginine translocation tat substrates in virulence of Yersinia
AVİCAN U., DORUK T., FAHLGREN A., FORSBERG A.
Microbial Pathogenesis and Host Response CSHL, Cold Spring Harbor, New York, United States Of America, 8 - 12 September 2015
Funded Projects
2020 - 2024
2020 - 2024Denizel Ortamlarda Plastiklerin Parçalanma Süreçlerini Hızlandıracak Kütinazların Fonksiyonel Metagenomik Yöntemlerle Keşfi ve Karakterizasyonu
TUBITAK Project , 3501 - National Young Researcher Career Development Program
Könen Adıgüzel S., Tunçer M., Kıdeyş A. E., Karahan A., Doruk T., Adıgüzel A. O. (Executive)
2021 - 2022
2021 - 2022Geobacillus kaustophilus'a (HTA426) ait hücre içi proteaz'ın (GK2549) klonlanması ve ifade ettirilmesi üzerine çalışmalar
Project Supported by Higher Education Institutions , BAP Other
Doruk T. (Executive)